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Salix's NDA for crofelemer in HIV-associated diarrhea assigned priority review status
Genentech's BLA for pertuzumab receives priority review status in previously untreated HER2-positive metastatic breast cancer indication
FDA reviewers questions efficacy of NeurogesX's Qutenza pain patch in proposed new use
Shire's Vyvanse approved for maintenance treatment in adults with ADHD
FDA accepts Ziopharm's IND application for oral formulation of Zymafos
Private FFS MA plans may be linked with higher costs for beneficiaries, GAO report shows
Pediatric subspecialty telephone consultations may be cost-saving for Medicaid, research reveals
Use of mental health services greater in health plans with parity in cost sharing, data find
Public opinions appear split on health care affordability, satisfaction, survey finds
In Brief: California Supreme Court
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AACAP 54th Annual Meeting
October 23-28, 2007 Boston, MA
Childhood ADHD associated with functional deficits in young adulthood, findings suggest
ADHD, medication use in children associated with emotional strain, poor health status among caregivers
Stigma associated with ADHD prevalent, may affect receptivity to treatment
OROS methylphenidate safely treats adult ADHD, trials show
Dexmethylphenidate extended release at daily doses as high as 30 mg yields improvements in teacher-rated reports of children with ADHD
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U.S. Psychiatric & Mental Health Congress 2007
October 11-14, 2007 Orlando, FL
Comorbidities extremely common in children with ADHD; effective patient management requires treating these illnesses as well, experts report
Methylphenidate transdermal system shows similar efficacy in male, female children with ADHD, although males may face greater risk of adverse events
Abuse potential with OROS methylphenidate lower than with other methylphenidate formulations
Stimulant dosing in adults with ADHD lower than effective levels
Lisdexamfetamine improves parent-rated measures of ADHD
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APA 2007 Annual Meeting - ADHD track
May 19-24, 2007 San Diego, CA
Interpatient pharmacokinetic variability lower in patients receiving lisdexamfetamine as compared with mixed amphetamine salts
OROS methylphenidate shows benefits in patients with ADHD who have comorbid mood, anxiety disorders, concomitant drug therapy in trial
Extended-release dexmethylphenidate effective in controlling ADHD in children with combined subtype
Long-term treatment with lisdexamfetamine safe, effective in children with ADHD
Children, adults, patients with substance use disorders can receive appropriate diagnosis, treatment for ADHD
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APA 2007 Annual Meeting - Insomnia track
May 19-24, 2007 San Diego, CA
Patients accurately self-identify middle-of-the-night insomnia; zolpidem improves insomnia in these patients, study data show
Ramelteon not associated with impairments in middle-of-the-night balance, mobility, memory performance among older adults with primary insomnia, data find
Ramelteon safe, effective in treatment of insomnia among women in multiple clinical trials
Eszopiclone does not impair next-day driving ability, cognition relative to placebo, researchers report
No evidence of dependence with zolpidem CR during long-term treatment, findings show
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APSS SLEEP 2007
June 9-14, 2007 Minneapolis, MN
New research offers insight into pathophysiology of insomnia, potential targets for treatment
Patients with insomnia, comorbid depression have more severe insomnia at baseline relative to patients with primary insomnia, other comorbidities
Sublingual transmucosal zolpidem effective, well-tolerated among individuals with MOTN insomnia, findings show
Insomnia represents potentially large financial liability for employers, research indicates
Eszopiclone demonstrates moderate to strong effect sizes on sleep outcomes relative to placebo in patients with primary insomnia, insomnia with comorbidities
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AGS 2007 Annual Scientific Meeting
May 2-6, 2007 Seattle, WA
IMPACT depression model twice as effective as usual care, successfully implemented in some organizations
Insomnia affects many older adults, needs to be treated
Once-daily duloxetine 60 mg effective treatment for MDD-related anxiety in older patients, study suggests
MDD not adequately recognized, treated in older adults, experts say
Clinicians should seek individualized treatment plans for geriatric patients with multiple comorbidities, according to experts
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AstraZeneca, Targacept's depression drug candidate misses goal in second Phase III study
Alexza's inhaled antipsychotic may cause respiratory failure, FDA reviewers warn
Actavis launches first generic version of Novartis' Ritalin LA
Alkermes commences Phase III study of schizophrenia drug candidate
FDA advisory panel supports approval of Alexza's inhaled antipsychotic
Mental health disorders increasingly affecting workers' productivity, well-being, OECD report indicates
Health system-related variables seem to influence likelihood of screening mammography among women with intellectual disabilities, findings suggest
Merck dissolves AD agreement with Acumen, signs PI3K inhibitor agreement with Exelixis
FDA advisory panel supports approval of Alexza's inhaled antipsychotic
Obesity associated with increased health costs in middle-aged women, even after adjusting for co-occurring depression, data suggest